Structure of a mutagen from roasted seeds of Moringa oleifera
Document Type
Article
Publication Date
1989
Abstract
A mutagenic compound was isolated from roasted seeds of Moringa oleifera Lam. Its structure has been elucidated by spectral analysis as 4(α-L-rhamnosyloxy)phenylacetonitrile. The results of the Micronucleus Test, an in vivo method, showed that the number of micronucleated polychromatic erythrocytes (PCE)/1000 PCE for this compound is higher than that of the solvent control, dimethylsulfoxide, and approximates that of the positive control, tetracycline. This indicates that 4(α-L-rhamnosyloxy)phenylacetonitrile is a genotoxic compound.
Recommended Citation
Villasenor, Irene M.; Finch, Paul; Lim-Sylianco, Clara; and Dayrit, Fabian M., (1989). Structure of a mutagen from roasted seeds of Moringa oleifera. Archīum.ATENEO.
https://archium.ateneo.edu/chemistry-faculty-pubs/114