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Decisions to give and receive help are often influenced by group memberships, social identities, and intergroup relations. Two studies were conducted to test how perceived political relations between countries are related to willingness to accept offers of intergroup help. Respondents in two low-income countries, the Philippines (N = 289) and Pakistan (N = 275), indicated their willingness to accept (or not) Covid-19 vaccine donations from two higher-status countries (China and the United States) during the Covid pandemic. Results showed that the perceived motivation of the outgroup nation for providing help was associated with rejection or acceptance of help, mediated by emotional reactions to the help. A perception that outgroup nations donate vaccines to demonstrate and assert their superiority and power, that they donate vaccines to keep the outgroup dependent on the ingroup, and a perception that they donate vaccines out of self-interest, were all associated with rejection of vaccine donations. A perception that donations by the outgroup are motivated by genuine concern for the ingroup was associated with acceptance of help. Findings confirm that political intergroup relations are related to attitudes about whether the ingroup nation should accept intergroup help or not. Theoretical and applied implications are discussed.